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Found 2 Enz. Inhib. hit(s) with Target = 'Inosine-5'-monophosphate dehydrogenase 2' and Ligand = 'BDBM50133727'
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50133727(1-(3-Cyano-1-methyl-1H-indol-6-yl)-3-phenyl-urea |...)
Affinity DataIC50:  630nMAssay Description:Inhibitory activity tested against inosine-5'-monophosphate dehydrogenase 2 (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50133727(1-(3-Cyano-1-methyl-1H-indol-6-yl)-3-phenyl-urea |...)
Affinity DataIC50:  722nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed