Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 1' and Ligand = 'BDBM50560888'
TargetInterleukin-1 receptor-associated kinase 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50560888(CHEMBL4749646)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged IRAK1 (194 to 712 residues) expressed in baculovirus expression system using 5-FAM-KKKVSRSGLYRS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50560888(CHEMBL4749646)
Affinity DataKd:  2.80E+3nMAssay Description:Displacement of polymer supported probe 25 binding to IRAK1 in human THP-1 cell lysates preincubated for 45 mins under shaking condition followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed