BDBM50560888 CHEMBL4749646
SMILES CC(C)c1ccn2ncnc(N[C@H]3CC[C@H](CC3)N3CCN(CC3)C(=O)CCC(=O)N3CCC(CCN4CCN(CC4)c4ccc5C(=O)N(C6CCC(=O)NC6=O)C(=O)c5c4)CC3)c12
InChI Key InChIKey=ZUODKONSNNHSAJ-AMLBMYBGSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50560888
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged IRAK1 (194 to 712 residues) expressed in baculovirus expression system using 5-FAM-KKKVSRSGLYRS...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant human full-length His-tagged IRAK4 expressed in baculovirus expression system using 5-FAM-IPTSPITTTYFFFKKK-COOH as substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of GSG2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of CDK11/cyclin C (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of CRBN (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 780nMAssay Description:Displacement of polymer supported probe 25 binding to GSG2 in human THP-1 cell lysates preincubated for 45 mins under shaking condition followed by p...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of NTRK3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 2.80E+3nMAssay Description:Displacement of polymer supported probe 25 binding to IRAK1 in human THP-1 cell lysates preincubated for 45 mins under shaking condition followed by ...More data for this Ligand-Target Pair
Affinity DataKd: 34nMAssay Description:Displacement of polymer supported probe 25 binding to IRAK3 in human THP-1 cell lysates preincubated for 45 mins under shaking condition followed by ...More data for this Ligand-Target Pair
Affinity DataKd: 3.60E+3nMAssay Description:Displacement of polymer supported probe 25 binding to IRAK4 in human THP-1 cell lysates preincubated for 45 mins under shaking condition followed by ...More data for this Ligand-Target Pair
Affinity DataKd: 1.40E+3nMAssay Description:Displacement of polymer supported probe 25 binding to CDK8 in human THP-1 cell lysates preincubated for 45 mins under shaking condition followed by p...More data for this Ligand-Target Pair
Affinity DataKd: >3.00E+4nMAssay Description:Displacement of polymer supported probe 25 binding to CDK11 in human THP-1 cell lysates preincubated for 45 mins under shaking condition followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of CDK8/cyclin C (unknown origin)More data for this Ligand-Target Pair