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Found 4 Enz. Inhib. hit(s) with Target = 'Interleukin-15' and Ligand = 'BDBM50238648'
TargetInterleukin-15(Homo sapiens)
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Curated by ChEMBL
LigandPNGBDBM50238648(CHEMBL4102828)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-15(Mus musculus)
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Curated by ChEMBL
LigandPNGBDBM50238648(CHEMBL4102828)
Affinity DataIC50:  2.11E+4nMAssay Description:Inhibition of IL-15 in mouse 32Dbeta cells assessed as decrease in cell growth in presence of IL2 incubated for 30 mins followed by IL2 addition and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-15(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50238648(CHEMBL4102828)
Affinity DataIC50:  2.25E+4nMAssay Description:Inhibition of IL-15 in mouse 32Dbeta cells assessed as decrease in cell growth in presence of RLI incubated for 30 mins followed by RLI addition and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-15(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50238648(CHEMBL4102828)
Affinity DataKd:  4.84E+4nMAssay Description:Binding affinity to recombinant human IL-15 by SPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed