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Found 2 Enz. Inhib. hit(s) with Target = 'Isoform TrkA-I of High affinity nerve growth factor receptor (TrkAI)' and Ligand = 'BDBM204845'
TargetIsoform TrkA-I of High affinity nerve growth factor receptor (TrkAI)(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM204845(US9242977, 72-7)
Affinity DataIC50:  30nMpH: 7.5Assay Description:TrkA-inhibiting activity was measured according to the following method using LanthaScreen kinase assay reagents (Invitrogen; Fluorescein-Poly GT, La...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform TrkA-I of High affinity nerve growth factor receptor (TrkAI)(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM204845(US9242977, 72-7)
Affinity DataIC50:  33nMAssay Description:TrkA kinase-inhibiting activity in cell systems was measured using CHO-K1 cells expressing human TrkA and NFAT-bla (CellSenser TrkA-NFAT-bla CHO-K1 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent