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Found 3 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50343624'
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50343624(5alpha-17-Allyl-14-hydroxy-6-oxo-4,5-epoxymorphina...)
Affinity DataKi:  0.280nMAssay Description:Displacement of [3H]U69563 from human kappa-opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50343624(5alpha-17-Allyl-14-hydroxy-6-oxo-4,5-epoxymorphina...)
Affinity DataIC50:  49nMAssay Description:Antagonist activity at human kappa-opioid receptor expressed in CHO cells assessed as inhibition of U69593-induced [35S]GTPgammaS binding after 60 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50343624(5alpha-17-Allyl-14-hydroxy-6-oxo-4,5-epoxymorphina...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human kappa-opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding after 60 mins by scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed