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Found 3 Enz. Inhib. hit(s) with Target = 'Kinesin-like protein KIF11' and Ligand = 'BDBM23777'
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institut De Biologie Structurale

LigandPNGBDBM23777((2R)-2-amino-3-[(2-methyl-1,1-diphenylpropyl)sulfa...)
Affinity DataKi:  150nM ΔG°:  -38.6kJ/molepH: 6.9 T: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institut De Biologie Structurale

LigandPNGBDBM23777((2R)-2-amino-3-[(2-methyl-1,1-diphenylpropyl)sulfa...)
Affinity DataKi:  175nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institut De Biologie Structurale

LigandPNGBDBM23777((2R)-2-amino-3-[(2-methyl-1,1-diphenylpropyl)sulfa...)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed