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Found 3 Enz. Inhib. hit(s) with Target = 'Leucine-rich repeat serine/threonine-protein kinase 2' and Ligand = 'BDBM522421'
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM522421(8-fluoro-2-[trans-3- fluroocyclopentyl]-1- [(2R,4R...)
Affinity DataIC50:  5.68nMAssay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM522421(8-fluoro-2-[trans-3- fluroocyclopentyl]-1- [(2R,4R...)
Affinity DataIC50:  200nMAssay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM522421(8-fluoro-2-[trans-3- fluroocyclopentyl]-1- [(2R,4R...)
Affinity DataIC50:  202nMAssay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent