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Found 8 Enz. Inhib. hit(s) with Target = 'Leukotriene B4 receptor 1/2' and Ligand = 'BDBM50215740'
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215740(CHEMBL48906)
Affinity DataIC50:  4nMAssay Description:Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215740(CHEMBL48906)
Affinity DataIC50:  4nMAssay Description:Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215740(CHEMBL48906)
Affinity DataIC50:  56nMAssay Description:Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215740(CHEMBL48906)
Affinity DataIC50:  56nMAssay Description:Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215740(CHEMBL48906)
Affinity DataIC50:  280nMAssay Description:Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215740(CHEMBL48906)
Affinity DataIC50:  280nMAssay Description:Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215740(CHEMBL48906)
Affinity DataIC50:  700nMAssay Description:Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophils in whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215740(CHEMBL48906)
Affinity DataIC50:  700nMAssay Description:Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophils in whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed