Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 5A' and Ligand = 'BDBM320423'
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene Quantical Research

US Patent
LigandPNGBDBM320423(2-[(2-chlorophenyl)-propoxy- methyl]-1H-pyrrolo[3,...)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene Quantical Research

US Patent
LigandPNGBDBM320423(2-[(2-chlorophenyl)-propoxy- methyl]-1H-pyrrolo[3,...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of recombinant human C-terminal FLAG-tagged KDM5A (1 to 1090 residues) expressed in baculovirus infected sf9 cells using biotinylated H3K4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene Quantical Research

US Patent
LigandPNGBDBM320423(2-[(2-chlorophenyl)-propoxy- methyl]-1H-pyrrolo[3,...)
Affinity DataKd:  530nMAssay Description:Binding affinity to ARID/PHD1/Zn binding domain truncated human N-terminal His-SUMO-tagged KDM5A (1 to 588 residues) expressed in Escherichia coli by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB