Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'MAP kinase-interacting serine/threonine-protein kinase 1 [1-424]' and Ligand = 'BDBM227721'
TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227721(3-bromo-n-(1h-indazol-5-yl)-1h-pyrazolo[3,4-d]pyri...)
Affinity DataIC50:  8nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227721(3-bromo-n-(1h-indazol-5-yl)-1h-pyrazolo[3,4-d]pyri...)
Affinity DataIC50:  14nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227721(3-bromo-n-(1h-indazol-5-yl)-1h-pyrazolo[3,4-d]pyri...)
Affinity DataIC50:  26nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent