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Found 6 Enz. Inhib. hit(s) with Target = 'Mast/stem cell growth factor receptor Kit' and Ligand = 'BDBM397897'
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM397897(US9994552, Compound 108)
Affinity DataIC50: <1nMAssay Description:Kit wild type assay: In each well of a 384-well plate, 0.2 ng/ul final (2 nM) of wild type Kit (Carna Bioscience 08-156) was incubated in a total of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM397897(US9994552, Compound 108)
Affinity DataKd:  4.40nMAssay Description:Binding affinity to KIT V816H mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM397897(US9994552, Compound 108)
Affinity DataKd:  11nMAssay Description:Binding affinity to KIT V559D mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM397897(US9994552, Compound 108)
Affinity DataKd:  130nMAssay Description:Binding affinity to KIT V559D/T670I mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM397897(US9994552, Compound 108)
Affinity DataKd:  20nMAssay Description:Binding affinity to KIT (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM397897(US9994552, Compound 108)
Affinity DataKd:  0.400nMAssay Description:Binding affinity to KIT D816V mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed