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Found 6 Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50329962'
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329962(CHEMBL404696 | N-((S)-1-(2-(1-((3R,4S)-1-tert-buty...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329962(CHEMBL404696 | N-((S)-1-(2-(1-((3R,4S)-1-tert-buty...)
Affinity DataIC50:  70nMAssay Description:Displacement of [125I]-NDP-R-MSH from human MC4R expressed in CHO cells after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329962(CHEMBL404696 | N-((S)-1-(2-(1-((3R,4S)-1-tert-buty...)
Affinity DataIC50:  70nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329962(CHEMBL404696 | N-((S)-1-(2-(1-((3R,4S)-1-tert-buty...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329962(CHEMBL404696 | N-((S)-1-(2-(1-((3R,4S)-1-tert-buty...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human MC4R expressed in CHO cells assessed as cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329962(CHEMBL404696 | N-((S)-1-(2-(1-((3R,4S)-1-tert-buty...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human MC4R expressed in CHO cells assessed as increase of alpha-MSH-stimulated cAMP release pretreated for 10 mins before alpha-M...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed