Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 5' and Ligand = 'BDBM50505941'
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50505941(CHEMBL4451125)
Affinity DataIC50:  76nMAssay Description:Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50505941(CHEMBL4451125)
Affinity DataIC50:  100nMAssay Description:Inhibition of ASK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50505941(CHEMBL4451125)
Affinity DataIC50:  8.16E+3nMAssay Description:Inhibition of V5 tagged human ASK1 expressed in HEK-293T cells assessed as reduction in T838 autophosphorylation incubated for 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed