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Found 8 Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50519927'
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50519927(CHEMBL4546925)
Affinity DataKi:  55nMAssay Description:Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in HEK293 cell membranes incubated for 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50519927(CHEMBL4546925)
Affinity DataKi:  55nMAssay Description:Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in HEK293 cells incubated for 120 mins by radiometric scintillation ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)TBA
LigandPNGBDBM50519927(CHEMBL4546925)
Affinity DataKi:  79nMAssay Description:Displacement of [125]IBNtxA from mouse MOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50519927(CHEMBL4546925)
Affinity DataKi:  560nMAssay Description:Binding affinity to MOP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50519927(CHEMBL4546925)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of MOP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(MOUSE)TBA
LigandPNGBDBM50519927(CHEMBL4546925)
Affinity DataIC50:  1.09E+4nMAssay Description:Antagonist activity at mouse MOR expressed in CHO cell membranes assessed as inhibition of DAMGO induced [35S]-GTPgammaS binding incubated for 60 min...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50519927(CHEMBL4546925)
Affinity DataEC50:  39nMAssay Description:Agonist activity at human recombinant mu opioid receptor expressed in CHO cells assessed as stimulation of cAMP accumulation incubated for 10 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)TBA
LigandPNGBDBM50519927(CHEMBL4546925)
Affinity DataEC50:  73nMAssay Description:Partial agonist activity at mouse MOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by sci...More data for this Ligand-Target Pair
In DepthDetails PubMed