Found 8 Enz. Inhib. hit(s) with Target = 'NAD-dependent protein deacylase sirtuin-6' and Ligand = 'BDBM50005711' TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
University Of Bayreuth
Curated by ChEMBL
University Of Bayreuth
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:Inhibition of full length SIRT6 (unknown origin) using acetylated H3K9 peptide as substrate after 2 hrs in presence of NADMore data for this Ligand-Target Pair
3D Structure (crystal)TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
University Of Bayreuth
Curated by ChEMBL
University Of Bayreuth
Curated by ChEMBL
Affinity DataKi: 2.02E+3nMAssay Description:Antagonist activity at adrenergic Alpha-1D receptor in rat aortaMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
University Of Bayreuth
Curated by ChEMBL
University Of Bayreuth
Curated by ChEMBL
Affinity DataKi: 4.62E+3nMAssay Description:Antagonist activity at adrenergic Alpha-1D receptor in rat aortaMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
University Of Bayreuth
Curated by ChEMBL
University Of Bayreuth
Curated by ChEMBL
Affinity DataKi: 4.50E+5nMAssay Description:Inhibition of human SIRT6 preincubated for 5 mins in presence of substrate followed enzyme addition measured after 5 to 10 mins in presence of NAD by...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
University Of Bayreuth
Curated by ChEMBL
University Of Bayreuth
Curated by ChEMBL
Affinity DataKd: 4.45E+5nMAssay Description:Binding affinity to recombinant human full length SIRT6 (1 to 355 residues) expressed in Escherichia coli M15 after 20 mins in presence of NAM by flu...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
University Of Bayreuth
Curated by ChEMBL
University Of Bayreuth
Curated by ChEMBL
Affinity DataKd: 3.30E+4nMAssay Description:Binding affinity to recombinant human full length SIRT6 (1 to 355 residues) expressed in Escherichia coli M15 after 20 mins in presence of ADP-ribose...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
University Of Bayreuth
Curated by ChEMBL
University Of Bayreuth
Curated by ChEMBL
Affinity DataKd: 2.90E+4nMAssay Description:Binding affinity to recombinant human full length SIRT6 (1 to 355 residues) expressed in Escherichia coli M15 after 20 mins in presence of ADP-ribose...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
University Of Bayreuth
Curated by ChEMBL
University Of Bayreuth
Curated by ChEMBL
Affinity DataKd: 2.27E+5nMAssay Description:Binding affinity to recombinant human full length SIRT6 (1 to 355 residues) expressed in Escherichia coli M15 after 20 mins by fluorescence-based SDS...More data for this Ligand-Target Pair
