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Found 6 Enz. Inhib. hit(s) with Target = 'Nicotinamide N-methyltransferase' and Ligand = 'BDBM50502439'
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Biokin

Curated by ChEMBL
LigandPNGBDBM50502439(CHEMBL4520769)
Affinity DataKi:  6.17E+3nMAssay Description:Inhibition of N-terminal His6-tagged wild type human NNMT expressed in Escherichia coli NiCo21(DE3) assessed as reduction in 1-methylquinolinium leve...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Biokin

Curated by ChEMBL
LigandPNGBDBM50502439(CHEMBL4520769)
Affinity DataKi:  6.17E+3nMAssay Description:Inhibition of N-terminal His6-tagged wild type human NNMT expressed in Escherichia coli NiCo21(DE3) assessed as reduction in 1-methylquinolinium leve...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Biokin

Curated by ChEMBL
LigandPNGBDBM50502439(CHEMBL4520769)
Affinity DataIC50:  1.49E+4nMAssay Description:Inhibition of wild-type human full length NNMT expressed in Escherichia coli BL21(DE3) cells assessed as reduction in 1-methyl-nicotinamide formation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Biokin

Curated by ChEMBL
LigandPNGBDBM50502439(CHEMBL4520769)
Affinity DataIC50:  2.92E+4nMAssay Description:Inhibitory activity against cell free dihydrofolate redutase (DHFR) from Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Biokin

Curated by ChEMBL
LigandPNGBDBM50502439(CHEMBL4520769)
Affinity DataIC50:  2.92E+4nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins by UHP-HILIC-MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Biokin

Curated by ChEMBL
LigandPNGBDBM50502439(CHEMBL4520769)
Affinity DataKd:  3.60E+4nMAssay Description:Binding affinity to wild-type human full length NNMT expressed in Escherichia coli BL21(DE3)-codonplus-RIL cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed