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Found 2 Enz. Inhib. hit(s) with Target = 'Nicotinamide N-methyltransferase' and Ligand = 'BDBM50502449'
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50502449(CHEMBL4474988)
Affinity DataIC50:  2.34E+4nMAssay Description:Inhibition of wild-type human full length NNMT expressed in Escherichia coli BL21(DE3) cells assessed as reduction in 1-methyl-nicotinamide formation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50502449(CHEMBL4474988)
Affinity DataKd:  1.24E+5nMAssay Description:Binding affinity to wild-type human full length NNMT expressed in Escherichia coli BL21(DE3)-codonplus-RIL cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed