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Found 4 Enz. Inhib. hit(s) with Target = 'Nociceptin receptor' and Ligand = 'BDBM21844'
TargetNociceptin receptor(Homo sapiens (Human))
Istituto Superiore Di Sanita

LigandPNGBDBM21844(8-[(1R,3aR)-2,3,3a,4,5,6-hexahydro-1H-phenalen-1-y...)
Affinity DataKi:  0.390nM ΔG°:  -53.2kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Istituto Superiore Di Sanita

LigandPNGBDBM21844(8-[(1R,3aR)-2,3,3a,4,5,6-hexahydro-1H-phenalen-1-y...)
Affinity DataKi:  0.390nMAssay Description:Binding affinity to human nociceptin opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Istituto Superiore Di Sanita

LigandPNGBDBM21844(8-[(1R,3aR)-2,3,3a,4,5,6-hexahydro-1H-phenalen-1-y...)
Affinity DataIC50:  4.40nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human NOP receptor expressed in human HEK293 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Istituto Superiore Di Sanita

LigandPNGBDBM21844(8-[(1R,3aR)-2,3,3a,4,5,6-hexahydro-1H-phenalen-1-y...)
Affinity DataEC50:  39nMAssay Description:Agonist activity at human nociceptin opioid receptor by GTPgamma(35)S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed