Affinity DataKi: 0.390nM ΔG°: -53.2kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Binding affinity to human nociceptin opioid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human NOP receptor expressed in human HEK293 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 39nMAssay Description:Agonist activity at human nociceptin opioid receptor by GTPgamma(35)S binding assayMore data for this Ligand-Target Pair