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Found 3 Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma [258-518,Y502F]' and Ligand = 'BDBM221229'
TargetNuclear receptor ROR-gamma [258-518,Y502F](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221229(US9303015, 3a | US9303015, 3b | US9303015, 3c)
Affinity DataIC50:  120nMAssay Description:The reporter assay was performed by transiently transfecting HEK293T cells with 5 μg of pBIND-RORγt LBD or pBIND-RORγt LBD-AF2 and 5 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [258-518,Y502F](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221229(US9303015, 3a | US9303015, 3b | US9303015, 3c)
Affinity DataIC50:  160nMAssay Description:The reporter assay was performed by transiently transfecting HEK293T cells with 5 μg of pBIND-RORγt LBD or pBIND-RORγt LBD-AF2 and 5 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [258-518,Y502F](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221229(US9303015, 3a | US9303015, 3b | US9303015, 3c)
Affinity DataIC50:  1.40E+3nMAssay Description:The reporter assay was performed by transiently transfecting HEK293T cells with 5 μg of pBIND-RORγt LBD or pBIND-RORγt LBD-AF2 and 5 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent