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Found 6 Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM50434481'
TargetOrexin receptor type 2(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50434481(CHEMBL2385132 | CHEMBL2385133 | CHEMBL2385134)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to orexin receptor 2 (unknown origin)More data for this Ligand-Target Pair
TargetOrexin receptor type 2(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50434481(CHEMBL2385132 | CHEMBL2385133 | CHEMBL2385134)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to orexin receptor 2 (unknown origin)More data for this Ligand-Target Pair
TargetOrexin receptor type 2(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50434481(CHEMBL2385132 | CHEMBL2385133 | CHEMBL2385134)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to orexin receptor 2 (unknown origin)More data for this Ligand-Target Pair
TargetOrexin receptor type 2(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50434481(CHEMBL2385132 | CHEMBL2385133 | CHEMBL2385134)
Affinity DataKi:  1.10nMAssay Description:Antagonist activity at OX2 receptor (unknown origin)More data for this Ligand-Target Pair
TargetOrexin receptor type 2(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50434481(CHEMBL2385132 | CHEMBL2385133 | CHEMBL2385134)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]4-(2,6-Difluoro-4-methoxybenzyl)-2-(5,6-dimethoxypyridin-3-yl)-2H-1,2,4-benzothiadiazin-3(4H)-one 1,1-dioxide from human wild-typ...More data for this Ligand-Target Pair
TargetOrexin receptor type 2(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50434481(CHEMBL2385132 | CHEMBL2385133 | CHEMBL2385134)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at OX2 receptor (unknown origin)More data for this Ligand-Target Pair