Found 9 Enz. Inhib. hit(s) with Target = 'Peroxisome proliferator-activated receptor alpha' and Ligand = 'BDBM28802'
Affinity DataIC50: 97nM EC50: 4nMpH: 8.0 T: 2°CAssay Description:For hPPAR alpha, percentage inhibition was calculated relative to unlabeled GW2331, which was used as the active site-specific competitive binder. Fl...More data for this Ligand-Target Pair
Affinity DataIC50: 97nMAssay Description:Binding affinity to human GST-tagged PPAR-alpha LBD expressed in Escherichia coli BL21 (DE3) PlysS after 30 mins in presence of fluorescein ligand FL...More data for this Ligand-Target Pair
Affinity DataEC50: 123nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataEC50: 144nMAssay Description:Agonist activity at mouse PPAR-alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 123nMAssay Description:Agonist activity at rat PPAR-alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Agonist activity at Gal4-tagged human PPAR-alpha expressed in HEK cells by transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataEC50: 145nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Mesocricetus auratus (golden hamster))
Bristol-Myers Squibb
Bristol-Myers Squibb
Affinity DataEC50: 178nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:Agonist activity at full length human PPAR-alpha transfected in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair