Compile Data Set for Download or QSAR
maximum 50k data
Found 7 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM50392138'
LigandPNGBDBM50392138(CHEMBL2152768)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50392138(CHEMBL2152768)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of PI3K p110delta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50392138(CHEMBL2152768)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of PI3K p110delta using PIP2 as substrate assessed as PIP3 formation by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50392138(CHEMBL2152768)
Affinity DataIC50:  4nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition measured after 60 mins in pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50392138(CHEMBL2152768)
Affinity DataIC50:  40nMAssay Description:Inhibition of PI3Kdelta-mediated AKT phosphorylation in B cells in presence of human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50392138(CHEMBL2152768)
Affinity DataIC50:  41nMAssay Description:Inhibition of PI3Kdelta in human whole blood assessed as upregulation of CD69More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50392138(CHEMBL2152768)
Affinity DataIC50:  41nMAssay Description:Inhibition of PI3Kdelta in human whole blood assessed as inhibition of CD69 production in B lymphocyte by immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed