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Found 2 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM50554790'
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Hefei Institutes Of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554790(CHEMBL4781849)
Affinity DataIC50:  14nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Hefei Institutes Of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554790(CHEMBL4781849)
Affinity DataEC50:  67nMAssay Description:Inhibition of PI3Kdelta in human Raji cells assessed as reduction in anti-IgM stimulated AKT T308 phosphorylation incubated for 1 hr by Western blot ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed