BDBM50554790 CHEMBL4781849
SMILES CC[C@@H](c1nc2cccc(F)c2c(=O)n1C1CC1)n1nc(-c2ccc(OC)c(F)c2)c2c(N)ncnc12
InChI Key InChIKey=HTUBTEAYSCSTIY-SFHVURJKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50554790
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Hefei Institutes Of Physical Science
Curated by ChEMBL
Hefei Institutes Of Physical Science
Curated by ChEMBL
Affinity DataEC50: 67nMAssay Description:Inhibition of PI3Kdelta in human Raji cells assessed as reduction in anti-IgM stimulated AKT T308 phosphorylation incubated for 1 hr by Western blot ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Hefei Institutes Of Physical Science
Curated by ChEMBL
Hefei Institutes Of Physical Science
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Hefei Institutes Of Physical Science
Curated by ChEMBL
Hefei Institutes Of Physical Science
Curated by ChEMBL
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Hefei Institutes Of Physical Science
Curated by ChEMBL
Hefei Institutes Of Physical Science
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) incubated for 20 to 30 mins by P450-Glo assayMore data for this Ligand-Target Pair
TargetCytochrome P450 2B6(Homo sapiens (Human))
Hefei Institutes Of Physical Science
Curated by ChEMBL
Hefei Institutes Of Physical Science
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2B6 (unknown origin) incubated for 20 to 30 mins by P450-Glo assayMore data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Hefei Institutes Of Physical Science
Curated by ChEMBL
Hefei Institutes Of Physical Science
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin) incubated for 20 to 30 mins by P450-Glo assayMore data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Hefei Institutes Of Physical Science
Curated by ChEMBL
Hefei Institutes Of Physical Science
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin) incubated for 20 to 30 mins by P450-Glo assayMore data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
Hefei Institutes Of Physical Science
Curated by ChEMBL
Hefei Institutes Of Physical Science
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin) incubated for 20 to 30 mins by P450-Glo assayMore data for this Ligand-Target Pair