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Found 1 Enz. Inhib. hit(s) with Target = 'Presenilin-1' and Ligand = 'BDBM50484465'
TargetPresenilin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50484465(CHEMBL1916331)
Affinity DataIC50:  8nMAssay Description:Inhibition of gamma-secretase-mediated cleavage of human amyloid beta protein expressed in human H4 cells assessed as reduction in amyloid beta42 pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed