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Found 3 Enz. Inhib. hit(s) with Target = 'Progesterone receptor' and Ligand = 'BDBM50121167'
TargetProgesterone receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50121167(5-fluoro-3-(2'-oxo-1',2'-dihydrospiro[cyclopentane...)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at progesterone receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProgesterone receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50121167(5-fluoro-3-(2'-oxo-1',2'-dihydrospiro[cyclopentane...)
Affinity DataIC50:  14nMAssay Description:Progesterone receptor antagonist activity based on its ability to block progesterone induced alkaline phosphatase in the human breast cancer cell lin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50121167(5-fluoro-3-(2'-oxo-1',2'-dihydrospiro[cyclopentane...)
Affinity DataIC50:  230nMAssay Description:Inhibition of 3 nM [3H]-R5020 binding to progesterone receptor of human T47D cell cytosolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed