Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP3 subtype' and Ligand = 'BDBM35861'
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Ono Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 35861BDBM35861(phenylpropanoic acid analogue, 5)
Affinity DataKi:  12nM EC50:  22nMAssay Description:Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Ono Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 35861BDBM35861(phenylpropanoic acid analogue, 5)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Ono Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 35861BDBM35861(phenylpropanoic acid analogue, 5)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Ono Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 35861BDBM35861(phenylpropanoic acid analogue, 5)
Affinity DataIC50: 580nMAssay Description:Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Ono Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 35861BDBM35861(phenylpropanoic acid analogue, 5)
Affinity DataIC50: 580nMAssay Description:Antagonist activity at mouse EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Ono Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 35861BDBM35861(phenylpropanoic acid analogue, 5)
Affinity DataIC50: 3.60E+3nMAssay Description:Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed