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Found 4 Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP3 subtype' and Ligand = 'BDBM50254841'
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254841(2-(3-(3,4-dichlorophenylthio)-1H-indol-4-yloxy)-N-...)
Affinity DataIC50:  0.300nMAssay Description:Antagonist activity at human EP3 receptor assessed as cAMP production by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254841(2-(3-(3,4-dichlorophenylthio)-1H-indol-4-yloxy)-N-...)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254841(2-(3-(3,4-dichlorophenylthio)-1H-indol-4-yloxy)-N-...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254841(2-(3-(3,4-dichlorophenylthio)-1H-indol-4-yloxy)-N-...)
Affinity DataIC50:  15.5nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed