Found 13 Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP4 subtype' and Ligand = 'BDBM50107283'
Affinity DataKi: 13nMAssay Description:Displacement of [3H]PGE from human EP4 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Antagonist activity at rat recombinant EP4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Antagonist activity at dog recombinant EP4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 448nMAssay Description:Antagonist activity at human EP4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 449nMAssay Description:Displacement of [3H]-PGE2 from recombinant human EP4 receptor expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting analy...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Antagonist activity at recombinant human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-stimulated cAMP accumulation by scinti...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Antagonist activity against human EP4 expressed in HEK293 cells assessed as inhibition of PGE2-stimulated production of cAMP incubated for 20 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Antagonist activity at human EP4 receptor in HEK293 cells assessed as inhibition of PGE2-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 689nMAssay Description:Displacement of [3H]-PGE2 from recombinant human EP4 receptor expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting analy...More data for this Ligand-Target Pair
Affinity DataIC50: 1.52E+3nMAssay Description:Antagonist activity at EP4 receptor in human whole blood assessed as reversal of inhibition of PGE2 mediated LPS-induced TNF alpha production pretrea...More data for this Ligand-Target Pair
Affinity DataIC50: 1.52E+3nMAssay Description:Antagonist activity against EP4 in human whole blood assessed as reversal of PGE2-mediated suppression of LPS-induced TNF-alpha production preincubat...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Antagonist activity at EP4 receptor in LPS-stimulated human whole blood assessed as inhibition of PGE2-induced TNF-alpha release pretreated for 30 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.61E+3nMAssay Description:Antagonist activity at EP4 receptor in LPS-stimulated human whole blood assessed as inhibition of PGE2-induced TNF-alpha reduction preincubated for 3...More data for this Ligand-Target Pair