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Found 2 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 1 [582-599]' and Ligand = 'BDBM11639'
TargetProstaglandin G/H synthase 1 [582-599](Homo sapiens (Human))
Shahid Beheshti University

LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  2.43E+4nMAssay Description:The ability of the test compounds to inhibit ovine COX-1 and COX-2 was determined using chemiluminescent enzyme assays kit according to our previousl...More data for this Ligand-Target Pair
In DepthDetails
TargetProstaglandin G/H synthase 1 [582-599](Homo sapiens (Human))
Shahid Beheshti University

LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50: >1.00E+5nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed