Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 2' and Ligand = 'BDBM50361591'
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Rottapharm Biotech

US Patent
LigandPNGBDBM50361591(CHEMBL1939678 | US9162979, 1-II)
Affinity DataIC50:  27nMT: 2°CAssay Description:The murine monocyte/macrophage cell line J774 is grown in Dulbecco's modified Eagle's medium (DMEM), enriched with glutamine (2 mM), HEPES (25 mM), p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50361591(CHEMBL1939678 | US9162979, 1-II)
Affinity DataIC50:  96nMAssay Description:Inhibition of COX-2-mediated PGE2 production in LPS-stimulated mouse J774 cells after 24 hrs by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed