Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM13389'
LigandPNGBDBM13389(4-{[(4-cyanophenyl)methoxy](1-methyl-1H-imidazol-5...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of Bovine farnesyl transeferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM13389(4-{[(4-cyanophenyl)methoxy](1-methyl-1H-imidazol-5...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of transfer of [3H]-FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine FTaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM13389(4-{[(4-cyanophenyl)methoxy](1-methyl-1H-imidazol-5...)
Affinity DataEC50:  110nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed