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Found 4 Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein phosphatase beta' and Ligand = 'BDBM359121'
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Aerpio Therapeutics

US Patent
LigandPNGBDBM359121(US10220048, Compound AA31 | US10952992, No. AA31 |...)
Affinity DataIC50:  0.0800nMAssay Description:HPTP-β inhibition can be tested by any method chosen by the formulator, for example, Amarasinge K. K. et al., “Design and Synthesis of Potent, N...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Aerpio Therapeutics

US Patent
LigandPNGBDBM359121(US10220048, Compound AA31 | US10952992, No. AA31 |...)
Affinity DataIC50:  0.0800nMAssay Description:Non-limiting examples of the HPTP-β IC50(μM) activity for illustrative compounds are listed in TABLE 2.More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Aerpio Therapeutics

US Patent
LigandPNGBDBM359121(US10220048, Compound AA31 | US10952992, No. AA31 |...)
Affinity DataIC50:  0.0800nMAssay Description:Non-limiting examples of the HPTPβ IC50 (μM) activity.More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Aerpio Therapeutics

US Patent
LigandPNGBDBM359121(US10220048, Compound AA31 | US10952992, No. AA31 |...)
Affinity DataIC50:  0.0800nMAssay Description:Non-limiting examples of the HPTP-β IC50 (μM) activity.More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent