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Found 4 Enz. Inhib. hit(s) with Target = 'Regulator of G-protein signaling 17' and Ligand = 'BDBM50456401'
TargetRegulator of G-protein signaling 17(Homo sapiens)
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50456401(IRIGENOL)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of RGS17 (unknown origin) GAP activity in presence of GTP by malachite green dye based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRegulator of G-protein signaling 17(Homo sapiens)
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50456401(IRIGENOL)
Affinity DataIC50:  4.72E+4nMAssay Description:Inhibition of wild type GST-tagged RGS17 (unknown origin) interaction with biotinylated Galphao after 30 mins in presence of AMF and GDP by AlphaScre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRegulator of G-protein signaling 17(Homo sapiens)
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50456401(IRIGENOL)
Affinity DataIC50:  8.18E+4nMAssay Description:Inhibition of RGS17 (unknown origin) C117A mutant interaction with biotinylated Galphao after 30 mins in presence of AMF and GDP by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRegulator of G-protein signaling 17(Homo sapiens)
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50456401(IRIGENOL)
Affinity DataKd:  7.10E+5nMAssay Description:Binding affinity to RGS17 (unknown origin) by ITC methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed