Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'SRSF protein kinase 1' and Ligand = 'BDBM221070'
TargetSRSF protein kinase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM221070(SPHINX | US9695160, SPHINX | US9796707, Reference ...)
Affinity DataIC50: <10nMAssay Description:Inhibition of SRPK1 (unknown origin) using SRSF1 Arg-Ser (RS) peptide (NH2-RSPSYGRSRSRSRSRSRSRSRSNSRSRSY-OH) as substrate incubated for 10 mins in pr...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSRSF protein kinase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM221070(SPHINX | US9695160, SPHINX | US9796707, Reference ...)
Affinity DataIC50:  440nMT: 2°CAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM221070(SPHINX | US9695160, SPHINX | US9796707, Reference ...)
Affinity DataIC50:  440nMAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM221070(SPHINX | US9695160, SPHINX | US9796707, Reference ...)
Affinity DataIC50:  880nMpH: 7.5 T: 2°CAssay Description:A reaction buffer containing 200 mM Tris pH 7.5, 100 mM MgCl2 and 0.1 mg/ml BSA was added to 43 μM SRSF1Arg-Ser (RS) peptide (NH2-RSPSYGRSRSRSRS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed