Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Sentrin-specific protease 1' and Ligand = 'BDBM103835'
TargetSentrin-specific protease 1(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM103835(SPI-10 | US11041859, Code SPI-10 | US9791447, Comp...)
Affinity DataIC50:  2.40E+3nMAssay Description:The binding of SPI-01 to the enzyme-substrate complex was investigated. CSP analysis was carried out on the 40 kDa complex of 15N-labeled full length...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSentrin-specific protease 1(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM103835(SPI-10 | US11041859, Code SPI-10 | US9791447, Comp...)
Affinity DataIC50:  2.40E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSentrin-specific protease 1(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM103835(SPI-10 | US11041859, Code SPI-10 | US9791447, Comp...)
Affinity DataIC50:  1.11E+4nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSentrin-specific protease 1(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM103835(SPI-10 | US11041859, Code SPI-10 | US9791447, Comp...)
Affinity DataIC50: >6.00E+7nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed