Found 6 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase B-raf' and Ligand = 'BDBM50075576' TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Umr Cnrs-Universit£
Curated by ChEMBL
Umr Cnrs-Universit£
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of B-Raf V600E mutant (unknown origin) assessed as inhibition of phosphorylation of peptide substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Umr Cnrs-Universit£
Curated by ChEMBL
Umr Cnrs-Universit£
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of wild type B-Raf (unknown origin) assessed as inhibition of phosphorylation of peptide substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Umr Cnrs-Universit£
Curated by ChEMBL
Umr Cnrs-Universit£
Curated by ChEMBL
Affinity DataIC50: <800nMAssay Description:Inhibition of B-Raf V600E mutant in human A375 cells assessed as phosphorylation of ERKMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Umr Cnrs-Universit£
Curated by ChEMBL
Umr Cnrs-Universit£
Curated by ChEMBL
Affinity DataEC50: <500nMAssay Description:Activation of tumorigenic wild type B-Raf in human IPC-298 cells with Ras mutation assessed as phosphorylation of ERKMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Umr Cnrs-Universit£
Curated by ChEMBL
Umr Cnrs-Universit£
Curated by ChEMBL
Affinity DataKd: 100nMAssay Description:Binding affinity to wild type B-Raf (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Umr Cnrs-Universit£
Curated by ChEMBL
Umr Cnrs-Universit£
Curated by ChEMBL
Affinity DataKd: 140nMAssay Description:Binding affinity to B-Raf V600E mutant (unknown origin)More data for this Ligand-Target Pair
