Found 6 Enz. Inhib. hit(s) with Target = 'Sphingosine 1-phosphate receptor 1' and Ligand = 'BDBM197654' 
Affinity DataIC50: 0.380nMAssay Description:Binding affinity to human S1P1More data for this Ligand-Target Pair
Affinity DataIC50: 57nMpH: 7.5Assay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1^108cells/pellet) were suspended in buffer containing 20 mM HEPES, pH 7...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0320nMAssay Description:Agonist activity at human S1P1 assessed as stimulation of cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 0.310nMAssay Description:Agonist activity at rat S1P1 expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgamma-S binding measured after 45 mins by liquid sci...More data for this Ligand-Target Pair
Affinity DataEC50: 57nMT: 2°CAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Ga1...More data for this Ligand-Target Pair
Affinity DataEC50: 0.590nMAssay Description:Agonist activity at human S1P1 expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgamma-S binding measured after 45 mins by liquid s...More data for this Ligand-Target Pair
