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Found 3 Enz. Inhib. hit(s) with Target = 'Steroid 17-alpha-hydroxylase/17,20 lyase' and Ligand = 'BDBM144614'
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))TBA
LigandPNGBDBM144614(US8969586, 1 | US9598436, 1)
Affinity DataIC50:  1nMAssay Description:Binding affinity against Melatonin receptor using ovine pars tuberalis membranes of the pituitary.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))TBA
LigandPNGBDBM144614(US8969586, 1 | US9598436, 1)
Affinity DataIC50:  1.10nMpH: 7.2 T: 2°CAssay Description:The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 μl prepared from 7.5 μl additions of microsomes (p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))TBA
LigandPNGBDBM144614(US8969586, 1 | US9598436, 1)
Affinity DataIC50:  1.10nMAssay Description:The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 μl prepared from 7.5 μl additions of microsomes (p...More data for this Ligand-Target Pair
In DepthDetails US Patent