Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Thromboxane-A synthase' and Ligand = 'BDBM50026486'
TargetThromboxane-A synthase(Human)
Nikken Chemicals

Curated by ChEMBL
LigandPNGBDBM50026486(7-Phenyl-7-pyridin-3-yl-hept-6-enoic acid | Isbogr...)
Affinity DataIC50: 0.900nMAssay Description:In vitro inhibition of thromboxane synthase (TXA2) in human platelet microsomes [reduced formation of TXB2 from prostaglandin H2(PGH2)]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Nikken Chemicals

Curated by ChEMBL
LigandPNGBDBM50026486(7-Phenyl-7-pyridin-3-yl-hept-6-enoic acid | Isbogr...)
Affinity DataIC50: 0.900nMAssay Description:Thromboxane A2 synthase inhibitory activity was measured from inhibition of thromboxane B2 production in human platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Nikken Chemicals

Curated by ChEMBL
LigandPNGBDBM50026486(7-Phenyl-7-pyridin-3-yl-hept-6-enoic acid | Isbogr...)
Affinity DataIC50: 51nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Nikken Chemicals

Curated by ChEMBL
LigandPNGBDBM50026486(7-Phenyl-7-pyridin-3-yl-hept-6-enoic acid | Isbogr...)
Affinity DataIC50: 51nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed