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Report error Found 9 Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM50440284'
TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50440284(CHEMBL2424780 | US10457681, Compound Vesatolimod |...)
Affinity DataEC50:  800nMAssay Description:HEK-Blue-hTLR7 cells were incubated at a density of 250,000˜450,000 cells/mL in a volume of 180 μL in a 96-well plate in Dulbecco's Mod...More data for this Ligand-Target Pair
TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50440284(CHEMBL2424780 | US10457681, Compound Vesatolimod |...)
Affinity DataEC50:  1.20E+3nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50440284(CHEMBL2424780 | US10457681, Compound Vesatolimod |...)
Affinity DataEC50:  100nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50440284(CHEMBL2424780 | US10457681, Compound Vesatolimod |...)
Affinity DataEC50:  517nMAssay Description:The compounds were gradient diluted with DMSO in 3-fold using liquid work station POD starting at a concentration of 10 mmol/L and 10 points were dil...More data for this Ligand-Target Pair
TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50440284(CHEMBL2424780 | US10457681, Compound Vesatolimod |...)
Affinity DataEC50:  291nMAssay Description:Agonist activity at human TLR7 receptorMore data for this Ligand-Target Pair
TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50440284(CHEMBL2424780 | US10457681, Compound Vesatolimod |...)
Affinity DataEC50:  1.20E+3nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue™ TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) ...More data for this Ligand-Target Pair
TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50440284(CHEMBL2424780 | US10457681, Compound Vesatolimod |...)
Affinity DataEC50:  1.20E+3nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue™ TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) ...More data for this Ligand-Target Pair
TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50440284(CHEMBL2424780 | US10457681, Compound Vesatolimod |...)
Affinity DataEC50:  800nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50440284(CHEMBL2424780 | US10457681, Compound Vesatolimod |...)
Affinity DataEC50:  1.20E+3nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue™ TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) ...More data for this Ligand-Target Pair