Found 7 Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM50543465' 
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at TLR7 (unknown origin) in PBMC cells assessed as reduction of IL-6 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Antagonist activity at TLR7 in human whole blood cells assessed as inhibition of gardiquimod induced IL-6 production by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human TLR7 overexpressed in HEK-Blue cells assessed as inhibition of gardiquimod-induced NFkappaB and AP-1 activation preincub...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Antagonist activity at TLR7 in human pDC assessed as inhibition of inactivated flu-virus induced IFN-alpha production incubated for 24 hrs measured b...More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Antagonist activity at TLR7 in mouse whole blood cells assessed as inhibition of gardiquimod induced IL-6 production by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Agonist activity at human TLR7 overexpressed in HEK293 cells assessed as NFkappaB expression by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.40nMAssay Description:Invivo antagonist activity at TLR7 in po dosed C57BL/6 mouse assessed as reduction of gardiquimod-induced IL-6 production pretreated for 30 mins foll...More data for this Ligand-Target Pair
