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Found 5 Enz. Inhib. hit(s) with Target = 'Transitional endoplasmic reticulum ATPase' and Ligand = 'BDBM50500324'
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50500324(CHEMBL3747448)
Affinity DataKi:  29nMAssay Description:Inhibition of His-tagged p97 (unknown origin) in presence of ATP and PNP by UV-transparent microplate assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50500324(CHEMBL3747448)
Affinity DataIC50:  6nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50500324(CHEMBL3747448)
Affinity DataIC50:  250nMAssay Description:Inhibition of p97 ATPase in human A549 cells assessed as reduction in p62 protein incubated for 6 hrs by immunofluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50500324(CHEMBL3747448)
Affinity DataIC50:  500nMAssay Description:Inhibition of p97 ATPase in human A549 cells assessed as accumulation of K48 poly-ubiquitinated proteins incubated for 6 hrs by immunofluorescence as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50500324(CHEMBL3747448)
Affinity DataIC50:  580nMAssay Description:Inhibition of p97 ATPase in human A549 cells assessed as accumulation of CHOP poly-ubiquitinated proteins incubated for 6 hrs by immunofluorescence a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed