TargetTranslocator protein(Rattus norvegicus (rat))
National Institute Of Radiological Sciences
Curated by ChEMBL
National Institute Of Radiological Sciences
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Displacement of [11C]-PK-11195 from TPSO in Sprague-Dawley rat brain homogenate after 30 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [3H]PK11195 from wild-type human TSPO expressed in HEK293 cells after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Displacement of [3H]PK11195 from wild-type human TSPO expressed in HEK293 cell membranes after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Displacement of [3H]PK11195 from human TSPO A147T mutant expressed in HEK293 cell membranes after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Displacement of [3H]PK11195 from human TSPO A147T mutant expressed in HEK293 cells after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
National Institute Of Radiological Sciences
Curated by ChEMBL
National Institute Of Radiological Sciences
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Test in vitro, for potential ability to displace [3H]1 from PBR in rat brain cortexMore data for this Ligand-Target Pair
Affinity DataKd: 2nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Escherichia coliMore data for this Ligand-Target Pair