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Found 1 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM288469'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM288469(4-(8-amino-1-(4-((4- cyanopyridin-2- yl)carbamoyl)...)
Affinity DataIC50:  0.410nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent