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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM295011'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Centaurus Biopharma

US Patent
LigandPNGBDBM295011(US10112922, Compound 1 | US9926299, 27 (R-isomer))
Affinity DataIC50: <100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Centaurus Biopharma

US Patent
LigandPNGBDBM295011(US10112922, Compound 1 | US9926299, 27 (R-isomer))
Affinity DataIC50: <100nMpH: 7.4Assay Description:The half inhibition concentrations (IC50 values) of the compounds disclosed herein on Btk were determined at both enzymatic level and cellular level:...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent