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Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM468316'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Carna Biosciences

US Patent
LigandPNGBDBM468316(4-{2-amino-4-[3- (6-cyclopropyl-8- fluoro-1-oxoiso...)
Affinity DataIC50:  0.520nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trade mark) MSA (commercially available kit manufactured by Carna Biosciences, In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Carna Biosciences

US Patent
LigandPNGBDBM468316(4-{2-amino-4-[3- (6-cyclopropyl-8- fluoro-1-oxoiso...)
Affinity DataIC50:  0.540nMAssay Description:Inhibition of human BTK-A using phosphorylated substrate in presence of ATP by microplate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Carna Biosciences

US Patent
LigandPNGBDBM468316(4-{2-amino-4-[3- (6-cyclopropyl-8- fluoro-1-oxoiso...)
Affinity DataIC50:  0.950nMAssay Description:Inhibition of human BTK C481S mutant using phosphorylated substrate in presence of ATP by microplate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed