Found 11 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM50553436' 
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged BTK expressed in baculovirus infected Sf21 insect cells using fluorescein-labeled ...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 1nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of BTK in human whole blood derived neutrophils assessed as reduction in SLE IC/FcgammaR-induced ROS generation preincubated for 30 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of BTK in human PBMC assessed as suppression of TNFalpha/FcgammaR-induced monocyte activation by measuring reduction in cytokine productio...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of BTK phosphorylation in human whole blood assessed as reduction in BTK phosphorylation incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of BTK in human PBMC assessed as reduction in anti-IgD-induced B cell activation preincubated for 30 mins followed by rabbit F(ab')2 anti-...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of BTK in human whole blood assessed as reduction in BTK phosphorylation measured after 30 mins by phosphotyrosine detection methodMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of BTK in DBA1 mouse whole blood assessed as reduction in BTK phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of BTK in human PBMC assessed as reduction in goat F(ab')2 anti-human IgM antibody-induced B cell activation measured after 3 days by cell...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of BTK in human Ramos cells assessed as reduction in BCR mediated PLCgamma2 phosphorylationMore data for this Ligand-Target Pair
Affinity DataKd: 0.300nMAssay Description:Binding affinity to wild-type human full length BTK (M1 to S659 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
