Found 6 Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase 7' and Ligand = 'BDBM50250947'
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged full length USP7 using di-ubiquitin as substrate preincubated for 10 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of native full length C-terminal USP7 (unknown origin) using ubiquitin-Rho110 as substrate pre-incubated for 1 hr followed by substrate ad...More data for this Ligand-Target Pair
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of recombinant USP7 (unknown origin) by mass spectrometry based activity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of human USP7 using UbA10 as substrate incubated for 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human USP7 using ubiquitin-Rho as substrate incubated for 1 hrsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.58E+3nMAssay Description:Inhibition of USP7 in human SJSA cells assessed as increase in ubiquitinated MDM2 level after 16 hrs in presence of MG132 by MSD assayMore data for this Ligand-Target Pair